Located in Rome, the very contemporary Hotel Twenty One features an elegant, upscale setting with fantastic views of the Pincian Hill and of Saint Peter's Cupola. Staying here will surely be an unforgettable experience. The most famous touring itineraries of art, culture, history and tradition can be easily reached from this exclusive boutique hotel, located in the city center of Rome, half way between the Vatican Museums and the Spanish Steps. This 4-star Hotel, unique for its modern, sophisticated style and for its attention to detail, is the ideal destination for those seeking a pleasant vacation and for those traveling on business.

BY TRAIN
From Rome's Termini train station, take the A-line subway towards Battistini and get off at Lepanto. Our hotel is located 300 meters (328 yards) away from this subway station. From Rome's Ostiense train station, take line 30 (Clodio) past 7 stops and get off at Piazza Cavour. Our hotel is located 350 meters (383 yards) away from this station.
BY AIR
Rome's Fiumicino airport is connected to the city by the highway and by a local train service, the Leonardo Express, with runs to Rome's Termini station every 30 minutes. Rome's Ciampino airport is only a few bus stops away from Anagnina, the fist station of the A-line subway. From here, it's a 20-minute ride to Termini.
BY CAR
Coming from the North via highway A1 (from Florence): Exit at Roma Nord and continue to Settebagni. Then, take Via Salaria and turn right on Via del Foro Italico towards S.Pietro. Coming from the South via highway A1: Exit at Roma Sud, then take the G.R.A. to exit 1. Follow Via Aurelia to Piazza Irnerio and the Vatican Walls.
GPS COORDINATES:
Latitude: 415431.83 N - Longitude: 122808.22 E

Saint Peter's Basilica and the Vatican Museums
The greatest Christian cathedral that features the famous cupola designed by Michelangelo, rising 136 meters (149 yards) above ground, this basilica contains some of the most famous art works in the world, such as Bernini's canopy and Michelangelo's Pietà. The Vatican Museums, renowned around the world for the precious works they contain, include the famous Sistine Chapel. They are located just 900 meters (984 yards) away from Hotel Twenty One.

Piazza del Popolo and the Pincian Hill
This famous square, designed by Neoclassical architect Giuseppe Valadier, features a uniquely elliptical shape that stretches out towards the terrace on the Pincian Hill and towards the Tiber River. Starting from this square, you can reach the capital city's most famous shopping destinations, such as Via del Babuino and Via Condotti, as well as one of Rome's most famous promenades, which leads to the Terrace on the Pincian Hill. They are located just 500 meters (984 yards) away from Hotel Twenty One.

Trinità dei Monti Church and the Spanish Steps
The itinerary to visit Baroque-era Rome starts from Piazza di Spagna that stretches out in front of the Pincian Hill and at the foot of the Spanish Steps. Here, you will see one of the most unique fountains of Rome, designed by Pietro Bernini: the "Fountain of the Old Boat". They are located 1.5 km (0.9 miles) away from Hotel Twenty One.

Castel Sant' Angelo
Shows, exhibitions, events, and theme visits in an imposing, suggestive scenario of history and architecture rising above the Tiber River. Located 1 km (0.9 miles) away from Hotel Twenty One. Villa Borghese and the Borghese Museum: buildings, sculptures, monuments, fountains, museums, art galleries, a biopark, ponds and Italian gardens surrounded by age-old trees and wide open spaces generate a charming balance of art and nature. The museum contains some priceless art works, such as Canova's “Paolina Bonaparte” and Caravaggio's “Madonna and Child with St. Anne (Dei Palafrenieri).” Located 2 km (0.9 miles) away from Hotel Twenty One.

Justice Palace
This is the building that currently hosts the Italian Supreme Court. Characterized by its majestic façade, it is locally known as the "Palazzaccio" (bad palace) for its severe appearance and function. Located just 500 meters (984 yards) away from Hotel Twenty One.