An unforgettable experience
in the heart of Rome

Located in Rome, the very contemporary Hotel Twenty One features an elegant, upscale setting with fantastic views of the Pincian Hill and of Saint Peter's Cupola. Staying here will surely be an unforgettable experience. The most famous touring itineraries of art, culture, history and tradition can be easily reached from this exclusive boutique hotel, located in the city center of Rome, half way between the Vatican Museums and the Spanish Steps. This 4-star Hotel, unique for its modern, sophisticated style and for its attention to detail, is the ideal destination for those seeking a pleasant vacation and for those traveling on business.

Special Offers

Best Available Rate Guarantee dal 30 al 31/12/2013

Hotel Twentyone offer a very special rates for your business travel dal 30 al 31/12/2013

dal 30 al 31/12/2013

Special offer Facebook Fan!! dal 30 al 20/04/2013

Events

Tips for a Very Romantic Valentine’s Day in Rome dal 14 al 14/02/2013

Depeche Mode - Rome 2013 dal 20 al 20/07/2013

Iggy Pop & The Stooges - Rome dal 30 al 04/07/2013

the smallest cinema in the world dal 30 al 30/11/2014

Rome suitable for children dal 10 al 30/11/2013

Harley-Davidson celebrates 110 years in Rome dal 13 al 16/06/2013

Bruce Springsteen - festival dal 11 al 11/07/2013

The Time Elevator Roma dal 01 al 30/11/2013

Rainbow Magicland dal 30 al 30/11/2013

The former factory of Birra Peroni - MACRO dal 30 al 31/12/2013

The Zoological Gardens dal 29 al 31/10/2013

What our clients say

★★★★★

Very nice hotel, very modern, free wifi in lobby & room, nice breakfast, close to subway. The h…

Very nice hotel, very modern, free wifi in lobby & room, nice breakfast, close to subway. The h

I read the reviews before selecting an hotel in rome, to tell the truth.. I dont understand the

I stayed here for my 30th birthday earlier in the year. I have been to Rome a number of times a

we just left a hotel we had booked which was nice (design)but the matress was HORRIBLE so had a

i love it! the place is fantastic, the staff very helpfull( we had a problem with our luggage i

This break was arranged by partner for my 21st. The hotel is very modern and on arrival we were

We stayed in a junior suite for 5 nights and loved it. The suite was spacious and exactly as sh

“rome tour” Hotel twenty one is well situated for all attractions , we walked to all of the

My wife and I spent a long anniversary weekend at Hotel Twentyone. Though our time was limited

“Very nice hotel in the city of Rome” The hotel is a pretty nice hotel with some unusually

Hotel Twenty One is a very contemporary, upscale 4-star hotel located in the city center of Rome, near the city's most famous places of interest, including religious, historical, artistic, tourist, shopping and environmental destinations, including the Vatican and Saint Peter's Basilica, Piazza del Popolo, the Spanish Steps, the Pincian Hill and Villa Borghese, all located within a short, easy walk from the hotel.