Rome is a treasure trove, a genuine open-air museum, a city where you can breathe art and history on every corner. Visiting Rome is always an evocative and charming experience, strolling among its monuments and artistic treasures is a unique and unforgettable emotion.
Hotel Twenty One’s strategic location allows you to visit the most important places in comfort and have easy access to museums, pubs and restaurants.
Our hotel is in fact in the Prati district, between the Vatican and Piazza del Popolo, only 400 metres from the “Lepanto” underground station. The location and amenities offered make this hotel the ideal choice for unforgettable stays in Rome.
The most popular itineraries of art, culture, history and tradition are easily reached from this exclusive boutique hotel, which is located halfway between the Vatican Museums and the Spanish Steps in Piazza di Spagna. This 4 star hotel, characterized by a modern and sophisticated style and attention to detail, is the ideal destination, both to spend a pleasant holiday and to cater for business needs.